Cart 2
  • pTH-Related Protein (1-16) (human, mouse, rat) peptide

pTH-Related Protein (1-16) (human, mouse, rat) peptide

Not For Human Use, Lab Use Only.

Cat.#: 312070

Size:

* Buy 1 get 1 free (?) What is TFA?

Special Price 202.40 USD

Availability: 1-2 weeks
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    pTH-Related Protein (1-16) (human, mouse, rat) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    AVSEHQLLHDKGKSIQ
  • Sequence
    H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-OH
  • Length (aa)
    16
  • Peptide Purity (HPLC)
    98.3%
  • Molecular Formula
    C77H128N24O25
  • Molecular Weight
    1790.01
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Schler et al. observed that pTHrP (1-16), an N-terminal fragment of pTH-related protein lacking a pTH/pTHrP-receptor binding domain and thus the biological activity on classical pTHrP target cells, could activate the cardiac ET-A receptor. On the other hand, Langlois et al. could not detect binding of the fragment to ET-A nor to the ET-B receptor.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • J.M.Moseley et al., Proc. Natl. Acad. Sci. USA, 84, 5048 (1987)
    • K.-D.Schler et al., Br. J. Pharmacol., 132, 427 (2001)
    • C.Langlois et al., Peptides, 26, 1436 (2005)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight

Peptide Property

  • Analysed Sequence:H-AVSEHQLLHDKGKSIQ-OH
  • Chemical Formula:C77H128N24O25
  • Sequence length:16
  • Extinction coefficient:0 M-1cm-1
  • GRAVY:-0.76
  • Mw average:1789.98
  • Theoretical pI:7.88
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"