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Product Name
Recombinant PRUN2 protein (His tag)
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Description
Recombinant Human PRUNE2 Protein Fragment (aa 1-355) - A highly stable and soluble fragment of Protein prune homolog 2 (BNIP2 motif-containing molecule at the C-terminal region 1), designed for structural and biochemical studies of this important cancer-related protein.
The full-length PRUNE2 protein plays a significant role in regulating differentiation, survival and aggressiveness of tumor cells, as evidenced by research findings (ECO:0000269|PubMed:16288218). This protein is localized in the cytoplasm, where it likely exerts its regulatory functions in cellular processes. The recombinant fragment (amino acids 1-355) represents a computationally optimized stable domain that maintains key structural features while offering enhanced solubility for experimental applications in cancer biology and protein interaction studies.
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Protein name
Protein prune homolog 2
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Uniprot ID
Q8WUY3
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Gene Name
PRUNE2; BMCC1; BNIPXL; C9orf65; KIAA0367
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-355 aa (Q8WUY3) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 42.18 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 47 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"