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  • Priscilicidin peptide

Priscilicidin peptide

Not For Human Use, Lab Use Only.

Cat.#: 319245

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* Buy 1 get 1 free (?) What is TFA?

Special Price 94.20 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    Priscilicidin peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    Fmoc-WWRR-NH2
  • Sequence
    Fmoc-Trp-Trp-Arg-Arg-NH2
  • Length (aa)
    4
  • Peptide Purity (HPLC)
    95.57%
  • Molecular Formula
    C49H57N13O6
  • Molecular Weight
    924.06
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Priscilicidin exhibited antimicrobial activity in the low micromolar range (under 50 μM) against Gram-positive bacteria (E. faecium, S. aureus, methicillin-resistant-S. aureus, S. pneumoniae) and fungal strains (C. albicans and fluconazole-resistant C. auris), with similar inhibitory concentrations to the indolicidin control. However, the Priscilicidin peptide was found less active against representative Gram-negative bacteria (E. coli, P. aeruginosa) with MICs and FACS results in the high micromolar range.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Cardoso P, Appiah Danso S, Hung A, Dekiwadia C, Pradhan N, Strachan J, McDonald B, Firipis K, White JF, Aburto-Medina A, Conn CE, Valéry C. Rational design of potent ultrashort antimicrobial peptides with programmable assembly into nanostructured hydrogels. Front Chem. 2023 Jan 13;10:1009468. doi: 10.3389/fchem.2022.1009468. PMID: 36712988; PMCID: PMC9881724.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"