Recombinant PRDC1 protein (His tag)

Recombinant PRDC1 protein (His tag)

Cat.#: 543720

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Product Information

  • Product Name
    Recombinant PRDC1 protein (His tag)
  • Documents
  • Description

    Recombinant Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1) fragment (amino acids 2-225), derived from Homo sapiens. This 224-amino acid fragment represents a stable, soluble domain optimized for structural and biochemical studies, enabling investigation of its ligand-binding properties despite minimal enzymatic activity.

    The full-length Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1) is a human protein with low, barely detectable phosphoribosyltransferase activity in vitro. It binds to GMP, IMP, and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP), but is not expected to contribute significantly to purine metabolism or GMP salvage pathways. The subcellular location is unspecified. This recombinant fragment provides a focused tool to explore its binding characteristics and structural features without interference from non-essential regions.

  • Protein name
    Phosphoribosyltransferase domain-containing protein 1
  • Uniprot ID
    Q9NRG1
  • Gene Name
    PRTFDC1; HHGP
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 2-225 aa (Q9NRG1) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 27.20 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 29 kDa band.
  • Purity
    >89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"