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Product Name
Recombinant PRDC1 protein (His tag)
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Description
Recombinant Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1) fragment (amino acids 2-225), derived from Homo sapiens. This 224-amino acid fragment represents a stable, soluble domain optimized for structural and biochemical studies, enabling investigation of its ligand-binding properties despite minimal enzymatic activity.
The full-length Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1) is a human protein with low, barely detectable phosphoribosyltransferase activity in vitro. It binds to GMP, IMP, and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP), but is not expected to contribute significantly to purine metabolism or GMP salvage pathways. The subcellular location is unspecified. This recombinant fragment provides a focused tool to explore its binding characteristics and structural features without interference from non-essential regions.
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Protein name
Phosphoribosyltransferase domain-containing protein 1
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Uniprot ID
Q9NRG1
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Gene Name
PRTFDC1; HHGP
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 2-225 aa (Q9NRG1) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 27.20 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 29 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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