Phytochelatin 2 peptide

Phytochelatin 2 peptide

• COA/MS/HPLC Report
• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

γ-Glu-Cys-γ-Glu-Cys-Gly

γ-Glu-Cys-γ-Glu-Cys-Gly

5

97.5%

C₁₈H₂₉N₅O₁₀S₂

539.58

Synthetic

Powder

Phytochelatins (PCs) are a family of thiol-rich peptides, with the general structure (γ-Glu-Cys) n -Gly, with n = 2−11, induced in plants upon exposure to excessive amounts of heavy metals and some metalloids, such as arsenic. Studies with Cd(II), Hg(II), and Pb(II) show that the synthetic (Glu-Cys)2Gly peptide exhibits metal-chelating properties similar to the phytochelatin (γ Glu-Cys)2Gly.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Dennis KK, Uppal K, Liu KH, Ma C, Liang B, Go YM, Jones DP. Phytochelatin database: a resource for phytochelatin complexes of nutritional and environmental metals. Database (Oxford). 2019 Jan 1;2019:baz083. doi: 10.1093/database/baz083. PMID: 31267134; PMCID: PMC6606759.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.