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Recombinant PGAM1 protein (His tag)

Recombinant PGAM1 protein (His tag)

Cat.#: 537589

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Special Price 294.7 USD

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Product Information

  • Product Name
    Recombinant PGAM1 protein (His tag)
  • Documents
  • Description

    Recombinant Phosphoglycerate Mutase 1 (PGAM1) Fragment (residues 2-254) is a high-purity protein designed for structural and biochemical studies. This fragment encompasses the stable catalytic domain of human PGAM1, facilitating research into its essential role in glycolysis and energy metabolism.

    Phosphoglycerate Mutase 1 (PGAM1) is a key glycolytic enzyme that catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate, a critical step in energy production. It also mediates the conversion between (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho-glyceroyl phosphate, utilizing 2,3-bisphosphoglycerate as a cofactor. This enzyme is vital for cellular metabolism, and its dysregulation has implications in various metabolic and disease contexts. The provided fragment (residues 2-254) represents a soluble, functionally relevant unit optimized for experimental applications.

  • Protein name
    Phosphoglycerate mutase 1
  • Uniprot ID
    P18669
  • Gene Name
    PGAM1; PGAMA
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 2-254 aa (P18669) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 30.33 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 32 kDa band.
  • Purity
    >87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"