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Product Name
Recombinant PEX26 protein (His tag)
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Description
Recombinant Human Peroxisome assembly protein 26 (Peroxin-26) Fragment (aa 31-246) - A highly stable and soluble protein fragment ideal for structural studies and biochemical analysis of peroxisomal assembly mechanisms.
Peroxisome assembly protein 26 (Peroxin-26), encoded by the PEX26 gene, serves as a critical peroxisomal docking factor that anchors PEX1 and PEX6 to peroxisome membranes. This anchoring function is essential for the formation of the PEX1-PEX6 AAA ATPase complex, which mediates the extraction of the PEX5 receptor from the peroxisomal membrane - a key step in peroxisome biogenesis and function. The protein is localized to the peroxisome membrane as a single-pass type II membrane protein. The provided recombinant fragment (amino acids 31-246) represents a computationally selected stable and soluble unit that maintains structural integrity for research applications investigating peroxisomal assembly pathways.
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Protein name
Peroxisome assembly protein 26
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Uniprot ID
Q7Z412
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Gene Name
PEX26
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 31-246 aa (Q7Z412) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 25.61 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 27 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"