Peg MGF peptide

Peg MGF peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

PEG-Suc-YQPPSTNKNTKSQrrKGSTFEEHK-NH2, r=D-Arg

PEG-Suc-Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-D-Arg-D-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-His-Lys-NH2

24

97.4%

C₁₂₁H₂₀₀N₄₂O₃₉

2948.15

Synthetic

Powder

Peg MGF is also named: peg MGF,Mechano growth factor,IGF-1 EC. PEG MGF is a splice variant of the IGF produced by a frame shift if the IGF gene and PEGylated to improve stability. PEG-MGF, or PEGylated Mechano Growth Factor, is a new and innovative form of the IGF produced by a frame shift if the IGF gene, namely Mechano Growth Factor (MGF), which is PEGylated to improve stability that outperforms natural MGF many times over. MGF is a splice variant of the IGF gene which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for growth of adult muscle. Natural MGF is made locally and does not travel into the bloodstream. Synthetic MGF is water based and when administered intramuscularly, travels into the bloodstream. MGF is only stable in the blood stream for only a few minutes. Research has shown that PEG-MGF helps increase the muscle stem cell count, so that more may fuse and become part of adult muscle cells.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Kim SJ, Park MH, Moon HJ, Park JH, Ko du Y, Jeong B. Polypeptide thermogels as a three dimensional culture scaffold for hepatogenic differentiation of human tonsil-derived mesenchymal stem cells. ACS Appl Mater Interfaces. 2014;6(19):17034-43.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.