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Recombinant PDE4C protein (His tag)

Recombinant PDE4C protein (His tag)

Cat.#: 540204

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Special Price 294.7 USD

Availability: 3-4 weeks
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Product Information

  • Product Name
    Recombinant PDE4C protein (His tag)
  • Documents
  • Description

    This recombinant protein product features a stable 335-amino acid fragment (residues 306-640) of human 3',5'-cyclic-AMP phosphodiesterase 4C (PDE4C), a key enzyme that hydrolyzes the second messenger cAMP. This carefully selected fragment represents a soluble and structurally stable region ideal for structural biology studies and biochemical characterization.

    The full-length 3',5'-cyclic-AMP phosphodiesterase 4C (PDE4C) is a cAMP-specific phosphodiesterase that plays a crucial role in cellular signaling by hydrolyzing the second messenger cAMP, a key regulator of numerous important physiological processes. This enzyme is localized to cell projections and cilia, suggesting specialized roles in these cellular compartments. By degrading cAMP, PDE4C helps terminate cAMP-mediated signaling cascades, making it an important regulator of various cellular responses.

  • Protein name
    3',5'-cyclic-AMP phosphodiesterase 4C
  • Uniprot ID
    Q08493
  • Gene Name
    PDE4C; DPDE1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 306-640 aa (Q08493) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 39.62 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 42 kDa band.
  • Purity
    >86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"