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Recombinant PARP4 protein (His tag)

Recombinant PARP4 protein (His tag)

Cat.#: 543859

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Special Price 294.7 USD

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Product Information

  • Product Name
    Recombinant PARP4 protein (His tag)
  • Documents
  • Description

    Recombinant PARP4 Fragment (aa 149-575) is a high-purity, 427-amino acid protein derived from human mono-ADP-ribosyltransferase PARP4. This fragment fully encompasses the PARP alpha-helical and catalytic domains, making it an ideal tool for investigating ADP-ribosylation mechanisms and domain-specific functions in cellular signaling and DNA repair pathways.

    PARP4 (Poly [ADP-ribose] polymerase 4) is a mono-ADP-ribosyltransferase that catalyzes the transfer of ADP-ribose moieties onto target proteins, playing a role in post-translational modifications involved in cellular regulation. It localizes to the cytoplasm, nucleus, and mitotic spindle apparatus, suggesting involvement in both nuclear processes and cytoskeletal organization during cell division. The full-length protein's association with mitotic spindles highlights its potential significance in cell cycle progression and structural dynamics.

  • Protein name
    Protein mono-ADP-ribosyltransferase PARP4
  • Uniprot ID
    Q9UKK3
  • Gene Name
    PARP4; ADPRTL1; KIAA0177; PARPL
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 149-575 aa (Q9UKK3) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 49.79 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 53 kDa band.
  • Purity
    >87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"