Parathyroid hormone (1 - 13) (human) peptide

Parathyroid hormone (1 - 13) (human) peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

H-SVSEIQLMHNLGK-OH

H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-OH

13

95.63%

C₆₂H₁₀₆N₁₈O₂₀S

1455.67

Synthetic

Powder

Parathyroid hormone (1 - 13) (human) is amino acids 1-13 of the N-terminus of parathyroid hormone and is a tryptic fragment sharing only 6 and 7 amino acids with the N-terminal tryptic peptides of parathyroid hormone related protein and parathyroid hormone (7–84) respectively. Parathyroid hormone (1 - 13) (human) has no substantial homology with any other trypsin digestion fragments of human proteins, making it a highly specific marker for full length parathyroid hormone (1–84).

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Lopez et al (2010) Selected reaction monitoring-mass spectrometric immunoassay responsive to parathyroid hormone and related variants. Clin Chem. 56(2) 281 PMID: 20022981
• Kumar et al (2010) Quantification of Serum 1-84 Parathyroid Hormone in Patients with Hyperparathyroidism by Immunocapture In Situ Digestion Liquid Chromatography-Tandem Mass Spectrometry, Clinical Chemistry, 56(2) 306 PMID: 20007860

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.