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Recombinant PAI2 protein (His tag)

Recombinant PAI2 protein (His tag)

Cat.#: 539696

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Special Price 294.7 USD

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Product Information

  • Product Name
    Recombinant PAI2 protein (His tag)
  • Documents
  • Description

    Recombinant Human Plasminogen Activator Inhibitor 2 (PAI-2) Fragment (aa 99-415) is a 317-amino acid protein designed for structural and biochemical studies. This fragment, derived from the SERPINB2 gene, represents a stable and soluble unit optimized for research applications, retaining key functional properties of the full-length protein.

    Plasminogen Activator Inhibitor 2 (PAI-2), also known as Serpin B2, is a key regulator of the fibrinolytic system that specifically inhibits urokinase-type plasminogen activator. Unlike the endothelial cell-derived PAI-1, PAI-2 is primarily monocyte-derived and plays distinct roles in cellular processes. The protein exhibits dual localization, functioning both in the cytoplasm and as a secreted protein in the extracellular space, indicating its involvement in both intracellular and extracellular regulatory pathways.

  • Protein name
    Plasminogen activator inhibitor 2
  • Uniprot ID
    P05120
  • Gene Name
    SERPINB2; PAI2; PLANH2
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 99-415 aa (P05120) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 37.53 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 39 kDa band.
  • Purity
    >90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"