Cart 2
  • PACAP-27, Adenylate cyclase-activating peptide-27

PACAP-27, Adenylate cyclase-activating peptide-27

Not For Human Use, Lab Use Only.

Cat.#: 311007

Size:

* Buy 1 get 1 free (?) What is TFA?

Special Price 264.00 USD

Availability: 3 weeks
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    PACAP-27, Adenylate cyclase-activating peptide-27
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    HSDGIFTDSYSRYRKQMAVKKYLAAVL
  • Sequence
    H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2
  • Length (aa)
    27
  • Peptide Purity (HPLC)
    95.5%
  • Molecular Formula
    C142H224N40O39S
  • Molecular Weight
    3147.65 net
  • Source
    Synthetic
  • Form
    Powder
  • Description
    PACAP-38 and its N-terminal fragment PACAP-27 are neuropeptides originally isolated from ovine hypothalamus, but also found in humans and rats. Both PACAP-27, which shows considerable homology with vasoactive intestinal polypeptide (VIP), and PACAP-38 stimulate adenylate cyclase much more potently than VIP. Specific PACAP receptors have been identified in different tissues and cell lines.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • A.Cauvin et al., Peptides, 11, 773 (1990)
    • K.Ogi et al., Biochem. Biophys. Res. Commun., 173, 1271 (1990)
    • C.Kimura et al., Biochem. Biophys. Res. Commun., 166, 81 (1990)
    • A.Miyata et al., Biochem. Biophys. Res. Commun., 170, 643 (1990)
    • P.Robberecht et al., FEBS Lett., 286, 133 (1991)
    • A.Arimura, Trends Endocrinol. Metab., 3, 288 (1992)
    • D.Spengler et al., Nature, 365, 170 (1993)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight

Peptide Property

  • Analysed Sequence:A
  • Chemical Formula:A
  • Sequence length:A
  • Extinction coefficient:A M-1cm-1
  • GRAVY:A
  • Mw average:A
  • Theoretical pI:A
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"