P1-Hp-1971 peptide

P1-Hp-1971 peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

TKPTLLGLPLGAGPAAGPGKR

Thr-Lys-Pro-Thr-Leu-Leu-Gly-Leu-Pro-Leu-Gly-Ala-Gly-Pro-Ala-Ala-Gly-Pro-Gly-Lys-Arg

21

95.7%

Synthetic

Powder

These H. pulchellus (Hp) peptides (AP2385 to AP2387) were named based on peptide identification number. There are 23% glycines and 19% prolines in the sequence. Active against S. aureus (MIC 8 uM) and E. coli (MIC 13 uM). There are more peptides reported in this peptidomic study. Their activity data are not available. P1-Hp-1971 was found in Skin Secretions, Hypsiboas pulchellus, South America.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Siano A, Húmpola MV, De oliveira E, et al. Antimicrobial peptides from skin secretions of Hypsiboas pulchellus (Anura: Hylidae). J Nat Prod. 2014;77(4):831-41.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.