OsRGF10 peptide

OsRGF10 peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

D{YSO3}AQPKTHT{Hyp}CHN-NH2

Asp-O-sulfo-L-tyrosine-Ala-Gln-Pro-Lys-Thr-His-Thr-L-Hydroxyproline-Cys-His-Asn-NH2

13

96.1%

C₆₄H₉₅N₂₁O₂₄S₂

1606.721

Synthetic

Powder

OsRGF10 is the dominant cold-resistant functional ortholog of tomato SlRGF10 in rice genome, with stronger cold-triggered expression in booting-stage anthers compared with OsRGF8. Post-translational tyrosine sulfation enables mature OsRGF10 to bind rice LRR-RLK RGFR-SERK co-receptor complex and activate downstream CNGC-mediated Ca²⁺ influx, which stabilizes tapetal developmental progress and prevents cold-mediated pollen degeneration. Transgenic rice with mild native-promoter-driven OsRGF10 overexpression achieves prominent cold tolerance in multi-site field trials: it improves seed-set percentage by 10%–25% under natural chilling stress and recovers approximately 18.3% of cold-induced grain yield loss. Constitutive high-level overexpression of OsRGF10 impairs normal rice tillering and fertility at optimal growth temperature. Either purified sulfated OsRGF10 or OsRGF8 can individually recover the cold-sensitive fertility defect of the osrgf8 osrgf10 double mutant rice.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Chen, S., Zou, Y., Cui, H. et al. Cold-induced peptide signalling secures pollen resilience and crop yield. Nature (2026). https://doi.org/10.1038/s41586-026-10603-7

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.