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  • Onc112 peptide

Onc112 peptide

Not For Human Use, Lab Use Only.

Cat.#: 318756

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Special Price 164.60 USD

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Product Information

  • Product Name
    Onc112 peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    VDKPPYLPRPRPPRrIYNr-NH2 (r=D-Arg)
  • Sequence
    H-Val-Asp-Lys-Pro-Pro-Tyr-Leu-Pro-Arg-Pro-Arg-Pro-Pro-Arg-D-Arg-Ile-Tyr-Asn-D-Arg-NH2
  • Length (aa)
    19
  • Peptide Purity (HPLC)
    95.2%
  • Molecular Formula
    C109H177N37O24
  • Molecular Weight
    2389.8
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Onc112, is a Proline-rich antimicrobial peptides (PrAMPs) that display potent activity against a diverse range of Gram-negative bacteria. It represents an exciting avenue for the development of future antimicrobials. Onc112 destabilizes the postinitiation complex by inducing dissociation of fMet-tRNAiMet.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Seefeldt AC, Nguyen F, Antunes S, et al. The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex.u00a0Nat Struct Mol Biol. 2015;22(6):470u2013475. doi:10.1038/nsmb.3034
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"