-
Product Name
Recombinant NXT1 protein (His tag)
- Documents
-
Description
Recombinant Human NTF2-related export protein 1 (NXT1/p15) fragment (aa 2-140) is a high-purity protein designed for studying nuclear export mechanisms. This fragment encompasses the complete NTF2 functional domain, making it an ideal tool for investigating specific domain functions in mRNA, tRNA, and snRNA transport.
NTF2-related export protein 1 (NXT1/p15), encoded by the NXT1 gene in Homo sapiens, functions as a critical stimulator of protein export for NES-containing proteins and facilitates the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer complex plays a key role in HSP70 mRNA export in collaboration with ALYREF/THOC4 and THOC5. Located in nuclear speckles and shuttling between the nucleus and cytoplasm, this protein is essential for intracellular trafficking processes. The provided fragment (aa 2-140) contains the complete NTF2 domain (aa 16-135), enabling focused research on domain-specific export functions.
-
Protein name
NTF2-related export protein 1
-
Uniprot ID
Q9UKK6
-
Gene Name
NXT1
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
DNA encoding 2-140 aa (Q9UKK6) were fused with 6His tag.
-
Protein Species
Human
-
Molecular weight
Predictes a molecular mass of 17.37 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 17 kDa band.
-
Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
-
Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"