Cart 2
  • Nuclear Factor NF-KB Inhibitor SN50 peptide

Nuclear Factor NF-KB Inhibitor SN50 peptide

Not For Human Use, Lab Use Only.

Cat.#: 310700

Size:

* Buy 1 get 1 free (?) What is TFA?

Special Price 254.20 USD

Availability: 3 weeks
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Nuclear Factor NF-KB Inhibitor SN50 peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    AAVALLPAVLLALLAPVQRKRQKLMP
  • Sequence
    H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Lys-Arg-Gln-Lys-Leu-Met-Pro-OH
  • Length (aa)
    26
  • Peptide Purity (HPLC)
    95.8%
  • Molecular Formula
    C129H230N36O29S
  • Molecular Weight
    2781.54
  • CAS No.
    213546-53-3
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Nuclear Factor NF-KB Inhibitor SN50 is a cell-permeable nuclear translocation inhibitor of the transcription factor NF-KB. It consists of the hydrophobic region (h-region) of the Kaposi fibroblast growth factor (K-FGF) signal sequence which mediates the cellular import of this peptide and the nuclear localization signal (NLS) of the NF-KB p50 subunit. The peptide inhibited nuclear translocation of NF-KB in LPS- or TNF-alpha-stimulated murine endothelial LE-II and human monocytic THP-1 cells. In seve
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Y.-Z.Lin et al., J. Biol. Chem., 270, 14255 (1995)
    • R.J.Salmond et al., Eur. J. Immunol., 32, 1737 (2002)
    • M.A.Robbins et al., Endocrinology, 144, 4616 (2003)
    • M.Guizzetti et al., Neuroscience, 120, 941 (2003)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight

Peptide Property

  • Analysed Sequence:H-AAVALLPAVLLALLAPVQRKRQKLMP-OH
  • Chemical Formula:C129H230N36O29S
  • Sequence length:26
  • Extinction coefficient:0 M-1cm-1
  • GRAVY:0.9
  • Mw average:2781.48
  • Theoretical pI:12.41
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"