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Recombinant NRP2 protein (His tag)

Recombinant NRP2 protein (His tag)

Cat.#: 539510

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Special Price 294.7 USD

Availability: 3-4 weeks
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Product Information

  • Product Name
    Recombinant NRP2 protein (His tag)
  • Documents
  • Description

    This recombinant protein product features a stable 158-amino acid fragment (residues 643-800) of human Neuropilin-2 (NRP2), a key receptor involved in vascular development and neuronal guidance. The fragment has been computationally optimized for structural stability and solubility, making it ideal for biochemical and structural studies.

    Neuropilin-2 (NRP2) functions as a high-affinity receptor for semaphorins 3C and 3F, VEGF-165 and VEGF-145 isoforms of vascular endothelial growth factor, and the PLGF-2 isoform of placental growth factor. The full-length protein is a single-pass type I membrane protein localized to the cell membrane, with some isoforms being secreted. Additionally, Neuropilin-2 serves as a receptor for human cytomegalovirus pentamer-dependent entry in epithelial and endothelial cells, highlighting its significance in both normal physiological processes and viral pathogenesis.

  • Protein name
    Neuropilin-2
  • Uniprot ID
    O60462
  • Gene Name
    NRP2; VEGF165R2
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 643-800 aa (O60462) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 19.77 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 21 kDa band.
  • Purity
    >85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"