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Product Name
Recombinant NPTXR protein (His tag)
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Description
Recombinant Neuronal Pentraxin Receptor (NPTXR) Fragment (aa 120-500) - A high-purity protein fragment specifically designed for studying the functional Pentraxin (PTX) domain, ideal for investigating synaptic remodeling and AMPA glutamate receptor clustering mechanisms.
The full-length Neuronal Pentraxin Receptor (NPTXR) is a single-pass type II membrane protein localized to the membrane in human cells. It plays a crucial role in mediating uptake of synaptic material during synapse remodeling and facilitates the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. This protein is essential for understanding neuronal connectivity and synaptic plasticity mechanisms in the central nervous system.
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Protein name
Neuronal pentraxin receptor
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Uniprot ID
O95502
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Gene Name
NPTXR
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 120-500 aa (O95502) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 43.50 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 45 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"