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  • Nigrocin-2 peptide

Nigrocin-2 peptide

Not For Human Use, Lab Use Only.

Cat.#: 309452

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* Buy 1 get 1 free (?) What is TFA?

Special Price 375.70 USD

Availability: 3 weeks
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Product Information

  • Product Name
    Nigrocin-2 peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    GLLSKVLGVGKKVLCGVSGLC
  • Sequence
    H-Gly-Leu-Leu-Ser-Lys-Val-Leu-Gly-Val-Gly-Lys-Lys-Val-Leu-Cys-Gly-Val-Ser-Gly-Leu-Cys-OH (disulfide bond: Cys15-Cys21)
  • Length (aa)
    21
  • Peptide Purity (HPLC)
    96.5%
  • Molecular Formula
    C90H162N24O24S2
  • Molecular Weight
    2028.5
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Note that nigrocin-2LVa, nigrocin-2 (or nigrocin-2N), and nigrocin-2HJ share the same primary structure. Active against M. luteus (MIC 2.5 ug/ml), Gram-negative S. dysenteriae, K. pneumoniae (MIC 10 ug/ml), P. aeruginosa (MIC 100 ug/ml), and S. typhimurium (MIC 22 ug/ml), and weakly active against C. albicans (MIC 150 ug/ml). Nigrocin 2 consists of an amphipathic alpha-helix from residue 3-18 in 50% TFE or SDS micelles. Updated 7/2013. Nigrocin-2 has Antimicrobial activity. The source of Nigrocin-2 is Pelophylax nigromaculatus (OLD Rana nigromaculata), Asia.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Park S, Park SH, Ahn HC, et al. Structural study of novel antimicrobial peptides, nigrocins, isolated from Rana nigromaculata. FEBS Lett. 2001;507(1):95-100.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Molecular Weight

Peptide Property

  • Analysed Sequence:H-GLLSKVLGVGKKVLCGVSGLC-OH
  • Chemical Formula:C90H162N24O24S2
  • Sequence length:21
  • Extinction coefficient:120 M-1cm-1
  • GRAVY:1.21
  • Mw average:2028.52
  • Theoretical pI:9.8
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"