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Recombinant NGN2 protein (His tag)

Recombinant NGN2 protein (His tag)

Cat.#: 548842

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Product Information

  • Product Name
    Recombinant NGN2 protein (His tag)
  • Documents
  • Description

    Recombinant Human Neurogenin-2 (NEUROG2) Fragment (aa 101-174): A high-purity protein fragment encompassing the complete bHLH domain, designed for targeted studies of transcriptional regulation and neuronal differentiation mechanisms.

    Neurogenin-2 (NGN-2) is a key transcriptional regulator in neuronal differentiation, functioning by binding to E-box DNA motifs (5'-CANNTG-3') to activate gene expression. As a nucleus-localized protein, it plays a critical role in neurogenesis, making it essential for research in neural development and cellular reprogramming. This fragment provides a focused tool for investigating the specific DNA-binding and dimerization functions mediated by its bHLH domain.

  • Protein name
    Neurogenin-2
  • Uniprot ID
    Q9H2A3
  • Gene Name
    NEUROG2; ATOH4; BHLHA8; NGN2
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 101-174 aa (Q9H2A3) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 10.38 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 10 kDa band.
  • Purity
    >87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"