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  • Neuropeptide EI-Gly-Arg-Arg-MCH (human, mouse, rat)

Neuropeptide EI-Gly-Arg-Arg-MCH (human, mouse, rat)

Not For Human Use, Lab Use Only.

Cat.#: 301157

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Product Information

  • Product Name
    Neuropeptide EI-Gly-Arg-Arg-MCH (human, mouse, rat)
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    EIGDEENSAKFPIGRRDFDMLRCMLGRVYRPCWQV
  • Sequence
    H-Glu-Ile-Gly-Asp-Glu-Glu-Asn-Ser-Ala-Lys-Phe-Pro-Ile-Gly-Arg-Arg-Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Gln-Val-OH
  • Length (aa)
    35
  • Peptide Purity (HPLC)
    96.5%
  • Molecular Formula
    C182H282N54O52S4
  • Molecular Weight
    4186.84
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Neuropeptide EI-Gly-Arg-Arg-MCH (human, mouse, rat) has been shown to be more potent in stimulating feeding in the rat than MCH (H-1482) following intracerebroventricular administration although it did not exhibit better agonist activity in in vitro assays. Its enhanced activity in feeding behaviour compared to MCH might be due to its reduced susceptibility to proteolytic degradation by MCH-degrading enzymes such as endopeptidase 24.11 and aminopeptidase M.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • A.Viale et al., J. Biol. Chem., 274, 6536 (1999)
    • L.Maulon-Feraille et al., J. Pharmacol. Exp. Ther., 302, 766 (2002)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Molecular Weight

Peptide Property

  • Analysed Sequence:H-EIGDEENSAKFPIGRRDFDMLRCMLGRVYRPCWQV-OH
  • Chemical Formula:C182H282N54O52S4
  • Sequence length:35
  • Extinction coefficient:7090 M-1cm-1
  • GRAVY:-0.59
  • Mw average:4186.76
  • Theoretical pI:6.45
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"