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Product Name
Recombinant NDUB4 protein (His tag)
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Description
This product is a recombinant fragment of the human NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (NDUFB4), spanning residues 2-87. It represents a stable and soluble unit of the protein, optimized for structural and biochemical studies of mitochondrial Complex I function in cellular respiration.
The full-length NDUFB4 protein is an accessory subunit of mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which plays a critical role in transferring electrons from NADH to ubiquinone during oxidative phosphorylation. While not directly involved in catalysis, it contributes to the structural and functional integrity of Complex I. This protein is localized to the inner mitochondrial membrane, with a single-pass transmembrane domain oriented toward the matrix side, supporting its role in the electron transport chain essential for ATP production.
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Protein name
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4
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Uniprot ID
O95168
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Gene Name
NDUFB4
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 2-87 aa (O95168) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 11.77 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 12 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"