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Product Name
Recombinant NCTR2 protein (His tag)
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Description
Recombinant Human NCR2 (NKp44) Fragment (aa 22-134) – a high-purity protein fragment designed for studying the Ig-like domain of the Natural cytotoxicity triggering receptor 2. This product enables targeted investigation of NK cell activation mechanisms and cytotoxicity pathways.
Natural cytotoxicity triggering receptor 2 (NCR2), also known as NKp44 or CD336, functions as a cytotoxicity-activating receptor that enhances the ability of activated natural killer (NK) cells to mediate tumor cell lysis. As a single-pass type I membrane protein located in the cell membrane, it plays a crucial role in immune surveillance and tumor recognition. The provided fragment specifically encompasses the Ig-like functional domain (aa 22-120), making it an ideal tool for domain-specific functional studies of NK cell activation mechanisms.
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Protein name
Natural cytotoxicity triggering receptor 2
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Uniprot ID
O95944
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Gene Name
NCR2; LY95
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 22-134 aa (O95944) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 14.40 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 14 kDa band.
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Purity
>88%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"