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Product Name
Recombinant MYOM1 protein (His tag)
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Description
Recombinant Human Myomesin-1 Fragment (405-832) is a high-purity protein designed for research on the structural and functional roles of the Fibronectin type-III domains within the M-band of sarcomeres. This 428-amino acid fragment provides a targeted tool for investigating domain-specific interactions in muscle biology.
Myomesin-1 is a major component of the vertebrate myofibrillar M band, where it plays a critical role in sarcomere organization and stability. It demonstrates dose-dependent binding to key myofibrillar proteins including myosin, titin, and light meromyosin. The protein is localized specifically to the cytoplasm within myofibrils, particularly in the sarcomere M line, where it contributes to the structural integrity and functional regulation of the contractile apparatus in muscle cells.
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Protein name
Myomesin-1
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Uniprot ID
P52179
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Gene Name
MYOM1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 405-832 aa (P52179) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 49.08 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 51 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"