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Product Name
Recombinant MYL6 protein (His tag)
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Description
Recombinant Human Myosin Light Polypeptide 6 (MYL6) Fragment (aa 2-151) - A high-purity protein fragment encompassing the complete EF-hand domains (1, 2, and 3) of the regulatory myosin light chain, ideal for functional studies of calcium-independent myosin regulation.
Myosin Light Polypeptide 6 (MYL6) serves as a regulatory light chain of myosin that does not bind calcium, distinguishing it from calcium-binding myosin light chains. As a component of both smooth muscle and nonmuscle myosin complexes, this protein plays a crucial role in regulating myosin motor activity and contractile functions. The full-length protein functions as part of the myosin heavy chain-light chain complex, where it contributes to the regulation of actin-based motility and cellular contractile processes without calcium dependency, suggesting alternative regulatory mechanisms in various cellular contexts.
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Protein name
Myosin light polypeptide 6
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Uniprot ID
P60660
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Gene Name
MYL6
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 2-151 aa (P60660) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 18.45 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 21 kDa band.
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Purity
>88%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"