Recombinant MYL3 protein (His tag)

Recombinant MYL3 protein (His tag)

Cat.#: 546714

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Product Information

  • Product Name
    Recombinant MYL3 protein (His tag)
  • Documents
  • Description

    Recombinant human Myosin light chain 3 (MYL3) fragment (residues 36-195), encompassing the complete EF-hand domains 1, 2, and 3. This high-purity protein is an essential tool for investigating the regulatory functions of cardiac and slow-twitch muscle myosin in calcium-independent mechanisms.

    Myosin light chain 3 (MYL3) serves as a regulatory light chain of myosin in human cardiac and slow-twitch skeletal muscle. It plays a critical role in modulating myosin motor activity and muscle contraction dynamics. Notably, this protein does not bind calcium, distinguishing its regulatory mechanism from calcium-dependent myosin light chains. The full-length protein is involved in fine-tuning contractile force and stability in ventricular muscle, making it significant for studies on cardiac function and muscular disorders.

  • Protein name
    Myosin light chain 3
  • Uniprot ID
    P08590
  • Gene Name
    MYL3
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 36-195 aa (P08590) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 19.92 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 23 kDa band.
  • Purity
    >90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"