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Product Name
Recombinant MYL3 protein (His tag)
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Description
Recombinant human Myosin light chain 3 (MYL3) fragment (residues 36-195), encompassing the complete EF-hand domains 1, 2, and 3. This high-purity protein is an essential tool for investigating the regulatory functions of cardiac and slow-twitch muscle myosin in calcium-independent mechanisms.
Myosin light chain 3 (MYL3) serves as a regulatory light chain of myosin in human cardiac and slow-twitch skeletal muscle. It plays a critical role in modulating myosin motor activity and muscle contraction dynamics. Notably, this protein does not bind calcium, distinguishing its regulatory mechanism from calcium-dependent myosin light chains. The full-length protein is involved in fine-tuning contractile force and stability in ventricular muscle, making it significant for studies on cardiac function and muscular disorders.
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Protein name
Myosin light chain 3
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Uniprot ID
P08590
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Gene Name
MYL3
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 36-195 aa (P08590) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 19.92 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 23 kDa band.
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Purity
>90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"