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Product Name
Recombinant MMP23 protein (His tag)
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Description
Recombinant Matrix Metalloproteinase-23 (MMP-23) Fragment (84-390) is a high-purity protein designed for studying the ShKT and Ig-like C2-type functional domains. This fragment supports research into protease functions and potassium channel regulation, offering a targeted tool for domain-specific investigations.
Matrix Metalloproteinase-23 (MMP-23) is a protease that may regulate the surface expression of certain potassium channels by retaining them in the endoplasmic reticulum. In humans, it is localized to the endoplasmic reticulum membrane as a single-pass type II membrane protein, with a potential secreted form generated through proteolytic cleavage. This protein plays a role in cellular processes involving proteolysis and channel modulation, highlighting its relevance in physiological and pathological contexts.
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Protein name
Matrix metalloproteinase-23
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Uniprot ID
O75900
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Gene Name
MMP23B; MMP21; MMP22
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 84-390 aa (O75900) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 37.14 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 37 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"