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  • Melimine peptide

Melimine peptide

Not For Human Use, Lab Use Only.

Cat.#: 318829

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* Buy 1 get 1 free (?) What is TFA?

Special Price 251.10 USD

Availability: 5 working days
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Product Information

  • Product Name
    Melimine peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-TLISWIKNKRKQRPRVSRRRRRRGGRRRR-OH
  • Sequence
    H-Thr-Leu-Ile-Ser-Trp-Ile-Lys-Asn-Lys-Arg-Lys-Gln-Arg-Pro-Arg-Val-Ser-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Gly-Arg-Arg-Arg-Arg-OH
  • Length (aa)
    29
  • Peptide Purity (HPLC)
    97.56%
  • Molecular Formula
    C158H290N74O35
  • Molecular Weight
    3786.45
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Melimine and Mel4 are chimeric cationic peptides with broad-spectrum antimicrobial activity. They neutralize LPS and disrupt cytoplasmic membranes within 30 seconds, releasing ATP and DNA/RNA.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Yasir M, Dutta D, Willcox MDP. Comparative mode of action of the antimicrobial peptide melimine and its derivative Mel4 against Pseudomonas aeruginosa [published correction appears in Sci Rep. 2019 Sep 10;9(1):13267]. Sci Rep. 2019;9(1):7063. Published 2019 May 8. doi:10.1038/s41598-019-42440-2
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight

Peptide Property

  • Analysed Sequence:H-TLISWIKNKRKQRPRVSRRRRRRGGRRRR-OH
  • Chemical Formula:C158H290N74O35
  • Sequence length:29
  • Extinction coefficient:5690 M-1cm-1
  • GRAVY:-2.27
  • Mw average:3786.45
  • Theoretical pI:13.48
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"