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Product Name
Recombinant MB3L1 protein (His tag)
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Description
Recombinant Human MBD3L1 (Methyl-CpG-binding domain protein 3-like 1) Fragment (residues 1-83) is a high-purity protein designed for structural and biochemical studies. This 83-amino acid fragment, computationally optimized for stability and solubility, enables researchers to investigate the transcriptional repressor functions of MBD3L1 in a manageable, functional unit.
Methyl-CpG-binding domain protein 3-like 1 (MBD3L1) is a transcriptional repressor involved in gene regulation, as supported by evidence from PubMed (12504854). The full-length protein localizes to the nucleus, specifically forming large foci, indicating its role in nuclear processes such as chromatin organization or transcriptional silencing. This recombinant fragment provides a targeted tool to explore MBD3L1's repressive mechanisms without domains that may complicate analysis, aligning with its native subcellular and functional context.
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Protein name
Methyl-CpG-binding domain protein 3-like 1
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Uniprot ID
Q8WWY6
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Gene Name
MBD3L1; MBD3L
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-83 aa (Q8WWY6) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 11.29 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 11 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"