Mastoparan-S peptide

Mastoparan-S peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

LRLKSIVSYAKKVL

Leu-Arg-Leu-Lys-Ser-Ile-Val-Ser-Tyr-Ala-Lys-Lys-Val-Leu

14

96.1%

Synthetic

Powder

APD analysis reveals that the sequence is 85.7% similar to insect Mastoparan B. Active against E. coli PTCC2433, K. pneumoniae PTCC4231, P. aeroginosa PTCC2834, B. subtilis PTCC4533, L. mesenteroides PTCC1445, B. cereus PTCC1435, A. niger, A. fumigates, and C. albicans (MIC 15-30 ug/ml). It showed 2.9% hemolysis at 100 ug/ml, much less hemolytic than the most similar peptide Mastoparan B. The source of Mastoparan-S is praying mantis, Sphodromantis viridis.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Zare-zardini H, Taheri-kafrani A, Ordooei M, Ebrahimi L, Tolueinia B, Soleimanizadeh M. Identification and Biochemical Characterization of a New Antibacterial and Antifungal Peptide Derived from the Insect Sphodromantis viridis. Biochemistry Mosc. 2015;80(4):433-40.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.