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  • (Lys1015-1024)-Thrombospondin-1 (1015-1024) (human, bovine, mouse) peptide

(Lys1015-1024)-Thrombospondin-1 (1015-1024) (human, bovine, mouse) peptide

Not For Human Use, Lab Use Only.

Cat.#: 310633

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* Buy 1 get 1 free (?) What is TFA?

Special Price 126.50 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    (Lys1015-1024)-Thrombospondin-1 (1015-1024) (human, bovine, mouse) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    KRFYVVMWKK
  • Sequence
    H-Lys-Arg-Phe-Tyr-Val-Val-Met-Trp-Lys-Lys-OH
  • Length (aa)
    10
  • Peptide Purity (HPLC)
    98.3%
  • Molecular Formula
    C68H105N17O12S
  • Molecular Weight
    1384.76
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Integrin-associated protein (IAP/CD47) agonist peptide, 4N1K (KRFYVVMWKK), derived from the cell binding domain of thrombospondin-1 (TS1). The peptide has been shown to stimulate integrin-dependent cell functions, including platelet aggregation.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • A.-G.Gao et al., J. Cell Biol., 135, 533 (1996)
    • X.-Q.Wang and W.A.Frazier, Mol. Biol. Cell, 9, 865 (1998)
    • C.A.Hillery et al., Blood, 94, 302 (1999)
    • J.Chung et al., Blood, 94, 642 (1999)
    • X.-Q.Wang et al., J. Cell Biol., 147, 389 (1999)
    • Y.Miyata et al., Clin. Cancer Res., 9, 1734 (2003)
    • T.-T.Fujimoto et al., J. Biol. Chem., 278, 26655 (2003)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight

Peptide Property

  • Analysed Sequence:H-KRFYVVMWKK-OH
  • Chemical Formula:C68H105N17O12S
  • Sequence length:10
  • Extinction coefficient:6970 M-1cm-1
  • GRAVY:-0.53
  • Mw average:1384.73
  • Theoretical pI:10.9
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"