Cart 2
  • Lys-Lys-IRS-1 (891-902) (dephosphorylated) (human) peptide

Lys-Lys-IRS-1 (891-902) (dephosphorylated) (human) peptide

Not For Human Use, Lab Use Only.

Cat.#: 314076

Size:

* Buy 1 get 1 free (?) What is TFA?

Special Price 137.00 USD

Availability: 1-2 weeks
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Lys-Lys-IRS-1 (891-902) (dephosphorylated) (human) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    KKKSPGEYVNIEFG
  • Sequence
    H-Lys-Lys-Lys-Ser-Pro-Gly-Glu-Tyr-Val-Asn-Ile-Glu-Phe-Gly-OH
  • Length (aa)
    14
  • Peptide Purity (HPLC)
    95.8%
  • Molecular Formula
    C73H114N18O22
  • Molecular Weight
    1595.82
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Substrate for the insulin-like growth factor 1 receptor (IGF-1R) tyrosine kinase domain (Km 26 ± 3.9 RM; kcat/Km 2.6 - 103 M-1min-1). The sequence is based on the phosphorylation site Tyr895 of the 185 kDa insulin receptor substrate-1 protein (IRS-1).
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • B.Xu et al., J. Biol. Chem., 270, 29825 (1995)
    • S.Favelyukis et al., Nat. Struct. Biol., 8, 1058 (2001)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight

Peptide Property

  • Analysed Sequence:H-KKKSPGEYVNIEFG-OH
  • Chemical Formula:C73H114N18O22
  • Sequence length:14
  • Extinction coefficient:1280 M-1cm-1
  • GRAVY:-1.09
  • Mw average:1595.78
  • Theoretical pI:9.56
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"