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  • LS-sarcotoxin peptide

LS-sarcotoxin peptide

Not For Human Use, Lab Use Only.

Cat.#: 318839

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* Buy 1 get 1 free (?) What is TFA?

Special Price 437.80 USD

Availability: 4 weeks
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Product Information

  • Product Name
    LS-sarcotoxin peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-GWLKKIGKKIERVGQHTRDATIQTIGVAQQAANVAATLK-NH2
  • Sequence
    H-Gly-Trp-Leu-Lys-Lys-Ile-Gly-Lys-Lys-Ile-Glu-Arg-Val-Gly-Gln-His-Thr-Arg-Asp-Ala-Thr-Ile-Gln-Thr-Ile-Gly-Val-Ala-Gln-Gln-Ala-Ala-Asn-Val-Ala-Ala-Thr-Leu-Lys-NH2
  • Length (aa)
    39
  • Peptide Purity (HPLC)
    95.2%
  • Molecular Formula
    C185H317N59O52
  • Molecular Weight
    4199.84
  • Source
    Synthetic
  • Form
    Powder
  • Description
    LS-sarcotoxin and LS-stomoxyn exhibit potent and selective activity against Gram-negative bacteria, with no cross-resistance to carbapenems, fluoroquinolones, or aminoglycosides. Concentrations of 4 or 8 mg/L inhibit 90% of clinical MDR isolates of Escherichia coli, Enterobacter cloacae, Acinetobacter baumannii, and Salmonella enterica. All-D homologues show markedly reduced activity, indicating a chiral target. In vitro studies reveal a good therapeutic index, no cytotoxicity or cardiotoxicity, and a broad-panel off-target profile.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Hirsch R, Wiesner J, Marker A, et al. Profiling antimicrobial peptides from the medical maggot Lucilia sericata as potential antibiotics for MDR Gram-negative bacteria. J Antimicrob Chemother. 2019;74(1):96-107. doi:10.1093/jac/dky386
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight

Peptide Property

  • Analysed Sequence:A
  • Chemical Formula:A
  • Sequence length:A
  • Extinction coefficient:A M-1cm-1
  • GRAVY:A
  • Mw average:A
  • Theoretical pI:A
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"