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Recombinant LRFN2 protein (His tag)

Cat.#: 543877

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Product Information

  • Product Name
    Recombinant LRFN2 protein (His tag)
  • Documents
  • Description

    Recombinant Human LRFN2 (Leucine-rich repeat and fibronectin type-III domain-containing protein 2) fragment (residues 21-379) is a high-purity protein designed for neuroscience and cell biology research. This fragment fully encompasses the LRRNT, LRRCT, and Ig-like functional domains, making it an ideal tool for studying neurite outgrowth, NMDA receptor regulation, and synaptic adhesion mechanisms.

    Leucine-rich repeat and fibronectin type-III domain-containing protein 2 (LRFN2), also known as Synaptic adhesion-like molecule 1, is a membrane protein that promotes neurite outgrowth in hippocampal neurons and enhances cell surface expression of NMDA receptor subunits GRIN1 and GRIN2A. It is localized to the postsynaptic cell membrane and synapses, where it may play a role in redistributing DLG4 to the cell periphery. As a single-pass type I membrane protein, LRFN2 functions in synaptic adhesion and neuronal development, making it a significant target for neurobiological research.

  • Protein name
    Leucine-rich repeat and fibronectin type-III domain-containing protein 2
  • Uniprot ID
    Q9ULH4
  • Gene Name
    LRFN2; KIAA1246; SALM1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 21-379 aa (Q9ULH4) were fused with N-terminal 6His tag.
  • Sequence 
    MNHKVHHHHH HGGSCPKYCV CQNLSESLGT LCPSKGLLFV PPDIDRRTVE LRLGGNFIIH ISRQDFANMT GLVDLTLSRN
TISHIQPFSF LDLESLRSLH LDSNRLPSLG EDTLRGLVNL QHLIVNNNQL GGIADEAFED FLLTLEDLDL SYNNLHGLPW
DSVRRMVNLH QLSLDHNLLD HIAEGTFADL QKLARLDLTS NRLQKLPPDP IFARSQASAL TATPFAPPLS FSFGGNPLHC
NCELLWLRRL ERDDDLETCG SPGGLKGRYF WHVREEEFVC EPPLITQHTH KLLVLEGQAA TLKCKAIGDP SPLIHWVAPD
DRLVGNSSRT AVYDNGTLDI FITTSQDSGA FTCIAANAAG EATAMVEVSI VQL
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 41.38 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 42 kDa band.
  • Purity
    >90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.
  • Validations

    Recombinant LRFN2 protein (His tag) SDS-PAGE

    Recombinant LRFN2 protein (His tag) SDS-PAGE

    M: Marker; Lane 1: RFN2; Lane 2: BSA

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"