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  • LIP1 (human) peptide

LIP1 (human) peptide

Not For Human Use, Lab Use Only.

Cat.#: 311770

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* Buy 1 get 1 free (?) What is TFA?

Special Price 283.60 USD

Availability: 3 weeks
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Product Information

  • Product Name
    LIP1 (human) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    ARSAPAAAIAARVAGQTRNITVDPRLFKK
  • Sequence
    H-Ala-Arg-Ser-Ala-Pro-Ala-Ala-Ala-Ile-Ala-Ala-Arg-Val-Ala-Gly-Gln-Thr-Arg-Asn-Ile-Thr-Val-Asp-Pro-Arg-Leu-Phe-Lys-Lys-OH
  • Length (aa)
    29
  • Peptide Purity (HPLC)
    95.7%
  • Molecular Formula
    C133H229N45O37
  • Molecular Weight
    3050.56
  • Source
    Synthetic
  • Form
    Powder
  • Description
    LIP1 is a peptide derived from the proregion of the nerve growth factor (NGF). The 29 amino acid peptide shows multiple biological activities. It induces F-actin rearrangement, phosphorylation of TrkA and Akt, exerts anti-proliferative effects on the mitogenic activity of estrogen and IGF in MCF-7 breast cancer cells, and is neuroprotective in vivo and in vitro.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • E.Dicou et al., J. Cell Biol., 136, 389 (1997)
    • E.Dicou, Biochem. Biophys. Res. Commun., 347, 833 (2006)
    • E.Dicou, J. Neuroimmunol., 194, 143 (2008)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight

Peptide Property

  • Analysed Sequence:H-ARSAPAAAIAARVAGQTRNITVDPRLFKK-OH
  • Chemical Formula:C133H229N45O37
  • Sequence length:29
  • Extinction coefficient:0 M-1cm-1
  • GRAVY:-0.13
  • Mw average:3050.51
  • Theoretical pI:12.41
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"