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  • Leptin (22-56) (human) peptide

Leptin (22-56) (human) peptide

Not For Human Use, Lab Use Only.

Cat.#: 309267

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* Buy 1 get 1 free (?) What is TFA?

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Product Information

  • Product Name
    Leptin (22-56) (human) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    VPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQK
  • Sequence
    H-Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys-OH
  • Length (aa)
    35
  • Peptide Purity (HPLC)
    95.4%
  • Molecular Formula
    C171H298N50O56
  • Molecular Weight
    3950.55
  • CAS No.
    183598-56-3
  • Source
    Synthetic
  • Form
    Powder
  • Description
    After central administration of this leptin fragment by feeding in the rat inhibition of food intake was observed. Leptin (22-56) depolarized rat hypothalamic paraventricular nucleus neurons. This leptin fragment was shown to enhance the proliferative activity of both the normal myometrium and myoma cells in primary culture.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • W.K.Samson et al., Endocrinology, 137, 5182 (1996)
    • J.E.Powis et al., Am. J. Physiol. Regulatory Integrative Comp. Physiol., 274, 1468 (1998)
    • A.Markowska et al., Int. J. Oncol., 27, 1505 (2005)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight

Peptide Property

  • Analysed Sequence:H-VPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQK-OH
  • Chemical Formula:C171H298N50O56
  • Sequence length:35
  • Extinction coefficient:0 M-1cm-1
  • GRAVY:-0.58
  • Mw average:3950.47
  • Theoretical pI:10.38
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"