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Product Name
Recombinant LBP protein (His tag)
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Description
Recombinant Human Lipopolysaccharide-binding protein (LBP) fragment (residues 26-481) is a high-quality, stable protein designed for research applications. This fragment captures the essential functional domain of LBP, enabling studies on innate immune responses and interactions with bacterial lipopolysaccharides (LPS).
Lipopolysaccharide-binding protein (LBP) is a key player in the innate immune response, primarily functioning to bind the lipid A moiety of bacterial lipopolysaccharides (LPS) found in Gram-negative bacteria. It enhances the affinity of CD14 for LPS, facilitating immune recognition and promoting cytokine release. LBP is secreted and can also associate with cytoplasmic granule membranes in polymorphonuclear leukocytes, underscoring its role in host defense mechanisms against bacterial infections.
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Protein name
Lipopolysaccharide-binding protein
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Uniprot ID
P18428
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Gene Name
LBP
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 26-481 aa (P18428) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 52.57 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 53 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"