-
Product Name
Human HAI-1/SPINT1 (His Tag) recombinant protein
- Documents
-
Description
Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14).
-
Protein name
Kunitz-type protease inhibitor 1
-
Protein short names
MANSC2; RP23-46P4.3; SPINT1; HAI-1; HAI1; HAI; UNQ223/PRO256
-
Uniprot ID
O43278
-
Gene Name
SPINT1; HAI1; UNQ223/PRO256
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the human SPINT1 isoform 2 (O43278-2) (Met 1-Val 433) was fused with a polyhistidine tag at the C-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human SPINT1 consists of 409 amino acids and predictes a molecular mass of 45.8 kDa. In SDS-PAGE under reducing conditions, rh SPINT1 migrates as an approximately 55 kDa band due to glycosylation.
-
Purity
> 96 % as determined by SDS-PAGE
-
Activity
Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2 (R&D Systems, Catalog # ES002). IC50 value is < 2nM.
-
Validations
Human HAI-1 / SPINT1 Protein (His Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"