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Product Name
Recombinant KLRG2 protein (His tag)
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Description
Recombinant Human KLRG2 (C-type lectin domain fragment) is a high-purity protein fragment encompassing amino acids 284-409, designed to include the complete C-type lectin functional domain (residues 300-405). This product serves as an essential tool for investigating the specific molecular interactions and biological roles of the C-type lectin domain in immune cell recognition and signaling pathways.
Killer cell lectin-like receptor subfamily G member 2 (KLRG2), also known as C-type lectin domain family 15 member B, is a membrane-anchored protein in humans that functions as a single-pass transmembrane protein. As a member of the C-type lectin receptor family, KLRG2 is implicated in immune regulation, particularly in natural killer (NK) cell and other immune cell activities, where it likely participates in pathogen recognition, cell adhesion, and modulation of immune responses. The protein's localization to the membrane supports its role in cell-surface interactions and signal transduction. The provid
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Protein name
Killer cell lectin-like receptor subfamily G member 2
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Uniprot ID
A4D1S0
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Gene Name
KLRG2; CLEC15B
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 284-409 aa (A4D1S0) were fused with C-terminal 6His tag.
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Sequence
MSRAGARCQQ CPPGWVLSEE HCYYFSAEAQ AWEASQAFCS AYHATLPLLS HTQDFLGRYP VSRHSWVGAW RGPQGWHWID EAPLPPQLLP EDGEDNLDIN CGALEEGTLV AANCSTPRPW VCAKGTQLEH HHHHH
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 15.61 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 16 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Validations
Recombinant KLRG2 protein (His tag) SDS-PAGE
M: Marker; Lane 1: KLRG2; Lane 2: BSA
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"