KF8K peptide

KF8K peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

H-KFEFKFEFKK-OH

H-Lys-Phe-Glu-Phe-Lys-Phe-Glu-Phe-Lys-Lys-OH

10

95.47%

C₇₀H₁₀₀N₁₄O₁₅

1377.62

Synthetic

Powder

KF8K peptide is a β-sheet-forming peptide, has the fiber edges covered by lysine residues. The addition the two lysine residues did not affect the ability of the new peptide, KFEFKFEFKK (KF8K), to form β-sheet-rich fibers and hydrogels provided that the overall charges carried by the peptide were kept the same. KF8K hydrogels were found to have significantly lower shear moduli and to align only at high shear rates and concentrations.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Jacek K. Wychowaniec, Andrew M. Smith, Cosimo Ligorio, Oleksandr O. Mykhaylyk, Aline F. Miller, and Alberto Saiani
• Biomacromolecules 2020 21 (6), 2285-2297

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.