Imcroporin peptide

Imcroporin peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

FFSLLPSLIGGLVSAIK

Phe-Phe-Ser-Leu-Leu-Pro-Ser-Leu-Ile-Gly-Gly-Leu-Val-Ser-Ala-Ile-Lys

17

96.6%

Synthetic

Powder

The synthetic form of the peptide is C-terminally amidated (Personal communication). Likely to form a helical structure based on helical wheel projection. The peptide showed good activity against G+ bacteria such as M. Luteus AB93113, B. thuringiensis AB93066, S. aureus AB94004, B. subtilis, including MRSA with MIC in the ragne of 20-50 ug/ml). Antimicrobial activity of this peptide was also demonstrated in vivo using an animal model:mouse infected with S. aureus. Updated 5/4/2012GW. Imcroporin has Antibacterial activity. Imcroporin was found in Isometrus maculates.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Zhao Z, Ma Y, Dai C, et al. Imcroporin, a new cationic antimicrobial peptide from the venom of the scorpion Isometrus maculates. Antimicrob Agents Chemother. 2009;53(8):3472-7.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.