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Product Name
Recombinant IGLC7 protein (His tag)
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Description
Recombinant Human Immunoglobulin lambda constant 7 (Ig lambda-7 chain C region) fragment (amino acids 1-106) is a high-purity protein designed for studying the Ig-like domain. This product enables researchers to investigate the structural and functional roles of the constant region in antibody-mediated immunity, providing a reliable tool for immunological and biochemical applications.
Immunoglobulin lambda constant 7 is part of the constant region of immunoglobulin light chains, which are glycoproteins produced by B lymphocytes. These immunoglobulins function as membrane-bound receptors or secreted antibodies, playing a critical role in humoral immunity. Membrane-bound forms act as antigen-specific receptors on B cells, triggering clonal expansion and differentiation into antibody-secreting plasma cells upon antigen binding. Secreted immunoglobulins mediate effector functions, leading to antigen elimination. The antigen-binding site is formed by the variable domain of a heavy chain paired with its as
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Protein name
Immunoglobulin lambda constant 7
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Uniprot ID
A0M8Q6
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Gene Name
IGLC7
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-106 aa (A0M8Q6) were fused with C-terminal 6His tag.
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Sequence
MSKIKGQPKA APSVTLFPPS SEELQANKAT LVCLVSDFNP GAVTVAWKAD GSPVKVGVET TKPSKQSNNK YAASSYLSLT PEQWKSHRSY SCRVTHEGST VEKTVAPAEC SLEHHHHHH
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 12.89 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 13 kDa band.
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Purity
>90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Validations
Recombinant IGLC7 protein (His tag) SDS-PAGE
M: Marker; Lane 1: IGLC7; Lane 2: BSA
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"