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Product Name
Recombinant IGLC1 protein (His tag)
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Description
Recombinant Human Immunoglobulin lambda constant 1 (IGLC1) fragment (amino acids 1-106) is a high-purity protein encompassing the complete Ig-like domain. This product is an essential tool for investigating antibody structure, B-cell receptor signaling, and humoral immune responses, offering researchers a defined antigen for functional and binding studies.
Immunoglobulin lambda constant 1 (IGLC1) constitutes the constant region of immunoglobulin light chains, which are critical components of antibodies produced by B lymphocytes. These immunoglobulins function as antigen receptors on B-cell membranes, triggering clonal expansion and differentiation into antibody-secreting plasma cells upon antigen binding. Secreted immunoglobulins execute the effector phase of humoral immunity, leading to targeted antigen elimination. Each immunoglobulin's antigen-binding site is formed by the variable domain of a heavy chain paired with its associated light chain variable domain, enabling high-affinity antigen recogn
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Protein name
Immunoglobulin lambda constant 1
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Uniprot ID
P0CG04
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Gene Name
IGLC1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-106 aa (P0CG04) were fused with C-terminal 6His tag.
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Sequence
MSKIKGQPKA NPTVTLFPPS SEELQANKAT LVCLISDFYP GAVTVAWKAD GSPVKAGVET TKPSKQSNNK YAASSYLSLT PEQWKSHRSY SCQVTHEGST VEKTVAPTEC SLEHHHHHH
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 12.98 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 15 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Validations
Recombinant IGLC1 protein (His tag) SDS-PAGE
M: Marker; Lane 1: IGLC1; Lane 2: BSA
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"