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  • Human P62;SQSTM1 Recombinant protein (GST tag)

Human P62;SQSTM1 Recombinant protein (GST tag)

Cat.#: 510838

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Product Information

  • Product Name
    Human P62;SQSTM1 Recombinant protein (GST tag)
  • Documents
  • Description
    Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. {, PubMed:10356400, PubMed:10747026, PubMed:11244088, PubMed:12471037, PubMed:15340068, PubMed:15802564, PubMed:15911346, PubMed:15953362, PubMed:16079148, PubMed:16286508, PubMed:19931284, PubMed:20168092, PubMed:24128730}.
  • Protein name
    Sequestosome-1
  • Protein short names
    ORCA; OSIL
  • Uniprot ID
    Q13501
  • Gene Name
    SQSTM1; ORCA; OSIL
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    1-440 aa encoded by BC017222 was inserted into PGEX-4T vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human P62;SQSTM1(Full length) SDS-PAGE

    Recombinant human P62;SQSTM1(Full length) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"