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Human ERN1/IRE1 (aa 465-977, His & GST Tag) recombinant protein

Cat.#: 503434

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Product Information

  • Product Name
    Human ERN1/IRE1 (aa 465-977, His & GST Tag) recombinant protein
  • Documents
  • Protein name
    Serine/threonine-protein kinase/endoribonuclease IRE1
  • Protein short names
    9030414B18RIK; IRE1P; C85377; MGC163277; IRE1A; IRE1ALPHA; MGC163279; HIRE1P; AI225830; ERN1; IRE1; RP23-418O11.11-001; FLJ30999
  • Uniprot ID
    O75460
  • Gene Name
    ERN1; IRE1
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human ERN1 isoform 1 (O75460-1) cytoplasmic domain (Pro 465-Leu 977) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human ERN1/GST chimera consists of 750 amino acids and has a calculated molecular mass of 86 kDa. It migrates as an approximately 90 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 80 % as determined by SDS-PAGE
  • Activity
    1. Kinase activity untested
    2. Measured by its nuclease activity to cleave Xbp1 single stem-loop mini-substrate.
  • Validations

    Human ERN1 / IRE1 Protein (aa 465-977, His & GST Tag) SDS-PAGE

    Human ERN1 / IRE1 Protein (aa 465-977, His & GST Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"