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  • Human CD38 (His & FLAG Tag) recombinant protein

Human CD38 (His & FLAG Tag) recombinant protein

Cat.#: 504219

Special Price 307.5 USD

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Product Information

  • Product Name
    Human CD38 (His & FLAG Tag) recombinant protein
  • Documents
  • Description
    The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.
  • Protein name
    ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
  • Protein short names
    ADPRC1; T10; CD38-RS1; CD38
  • Uniprot ID
    P28907
  • Gene Name
    CD38
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain of human CD38 (NP_001766.2) (Val 43 – Ile 300) was fused with a polyhistidine tag and a flag tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human CD38 comprises 285 amino acids with a predicted molecular mass of 33.2 kDa. As a result of glycosylation, rhCD38 migrates as an approximately 42-45 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 93 % as determined by SDS-PAGE
  • Validations

    Human CD38 Protein (His & FLAG Tag) SDS-PAGE

    Human CD38 Protein (His & FLAG Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"