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Product Name
Recombinant HSF2 protein (His tag)
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Description
Introducing the recombinant Heat Shock Factor Protein 2 (HSF2) fragment (residues 1-188), a high-quality protein product designed for structural and biochemical research. This fragment represents a stable and soluble unit of human HSF2, optimized for experimental applications in studying heat shock response mechanisms.
Heat Shock Factor Protein 2 (HSF2) is a DNA-binding protein that specifically recognizes and binds to heat shock promoter elements (HSE), playing a critical role in activating transcription in response to cellular stress. In higher eukaryotes, HSF2 remains inactive in the cytoplasm under normal growth conditions and translocates to the nucleus upon heat shock activation to regulate gene expression. This dynamic subcellular localization underscores its importance in cellular stress adaptation and homeostasis.
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Protein name
Heat shock factor protein 2
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Uniprot ID
Q03933
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Gene Name
HSF2; HSTF2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-188 aa (Q03933) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 23.75 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 24 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"