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Product Name
Recombinant HNRH2 protein (His tag)
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Description
Recombinant Human Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) Fragment (aa 1-186) – a high-purity protein fragment encompassing the RRM 1 domain, engineered for functional studies of RNA binding and pre-mRNA processing mechanisms.
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) is a key component of hnRNP complexes in human cells, which serve as essential substrates for pre-mRNA processing events required to generate functional, translatable mRNAs. It specifically binds poly(RG) sequences, contributing to RNA metabolism and regulatory functions. The protein is localized predominantly in the nucleus and nucleoplasm, where it participates in nucleic acid interactions critical for gene expression. This recombinant fragment, spanning residues 1-186 and containing the RRM 1 domain, enables targeted investigation into domain-specific roles in RNA binding and processing pathways.
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Protein name
Heterogeneous nuclear ribonucleoprotein H2
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Uniprot ID
P55795
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Gene Name
HNRNPH2; FTP3; HNRPH2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-186 aa (P55795) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 22.75 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 24 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"